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Tapentadol, a pain-relief medication, typically stays in urine for around 2 to 3 days after the last dose, though this duration can vary depending on factors like dosage, metabolism, and individual health conditions. As an opioid analgesic, tapentadol is often prescribed for moderate to severe pain, and it works by binding to opioid receptors and inhibiting norepinephrine reuptake, providing effective relief.
For most individuals, tapentadol reaches peak concentration in the blood within 1.25 hours, with a half-life of approximately 4 hours. However, the body eliminates it gradually, so small traces can remain detectable in urine up to 72 hours.
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